18 'Grey's Anatomy' storylines that didn't sit well with fans

by Julie Sprankles
Sep 22, 2016 at 7:00 p.m. ET

The short-lived pairing of BFFs George and Izzie was the worst. No chemistry, not believable... just ugh.

1 /17: Izzie's ghost sex

1/17 :Izzie's ghost sex

Not that we blame Izzie for wanting to have hot sex with Denny, but doing the deed with a ghost was bizarre. 

2 /17: RIP, George

2/17 :RIP, George

It sucked enough when lovable George decided to join the military. Did he seriously have to get hit by a bus?!

3 /17: Ava, aka 'Jane Doe'

3/17 :Ava, aka 'Jane Doe'

Not only did the ferry crash storyline eat up too much time, but Alex's Jane Doe wound up being wildly unstable. 

4 /17: 'Intern Fight Club'

4/17 :'Intern Fight Club'

Mer's childhood friend Sadie organized an intern ring of illicit surgeries on each other, and it was kinda silly.

5 /17: Kiss from a Rose

5/17 :Kiss from a Rose

We love Shonda Rhimes, but what was she thinking having Derek hook up with irksome nurse Rose?

6 /17: Dr. Hahn

6/17 :Dr. Hahn

Whether you loved this badass surgeon or hated her, you were likely unsatisfied with her random and abrupt exit.

7 /17: Sloan's Sloan

7/17 :Sloan's Sloan

Who could wait for Sloan's surprise daughter, Sloan, to leave? She ended up being such a bad apple. 

8 /17: Owen's shocking affair

8/17 :Owen's shocking affair

After everything, how could Owen have cheated on Yang? We weren't ready for this relationship to end.

9 /17: Bailey's OCD

9/17 :Bailey's OCD

Due to mounting pressure, Bailey suffered a serious OCD breakdown that seemingly came out of nowhere. 

10 /17: Arizona steps out on Callie

10/17 :Arizona steps out on Callie

Shippers were none too happy when Arizona broke Callie's heart by hooking up with visiting surgeon, Lauren. 

11 /17: Leah and Arizona's fling

11/17 :Leah and Arizona's fling

As adorable as Arizona is, hooking up with resident Leah was morally dubious and, well, nobody really dug it.

12 /17: Jackson and April's big loss

12/17 :Jackson and April's big loss

There were not enough tears in the world to deal with the diagnosis and death of Jackson and April's baby.

13 /17: Unlucky Penny

13/17 :Unlucky Penny

As if Derek's death wasn't enough, one of his inept doctors ends up dating Callie and on Mer's rotation. WTF?

14 /17: The exodus of Yang

14/17 :The exodus of Yang

"He is not the sun... you are." *sobs* Mer needs her person back. Ya hear, Shonda Rhimes?

15 /17: Say it ain't so, McDreamy!

15/17 :Say it ain't so, McDreamy!

Do I even have to explain this one? No one, and I mean no one, was on board with Derek's sudden death.

16 /17: Callie's low-key send-off

16/17 :Callie's low-key send-off

For a character as beloved as Callie was, she sure didn't get much of a send-off. Do-over? 

17 /17: That #Meriggs kiss, tho

17/17 :That #Meriggs kiss, tho

To be clear, that kiss had us all feelin' some kind of way. But we're into it now, right?