Demi Moore hooks up with Jennifer Aniston in Lifetime movie Five

Oct 3, 2011 at 6:53 p.m. ET

Jennifer Aniston, Alicia Keys, Demi Moore, Patty Jenkins and Penelope Spheeris step behind the camera to take on breast cancer with Five star-studded casts. SheKnows has Lifetime's extended Five trailer here!

Last week had everyone talking about the drama brewing between Demi Moore and Ashton Kutcher, including Kutcher's rebuttal and their Kabala date night. The week before, it was all about Brad Pitt's Jennifer Aniston comments. SheKnows kicks off Breast Cancer Awareness month with a new sneak peek of some heftier drama: the Lifetime original movie Five, directed by Moore, Aniston, Alicia Keys, Patty Jenkins and Penelope Spheeris.

Jennifer Aniston and Demi Moore go behind the camera for Lifetime's Five

The Lifetime original movie is an anthology of five shorts that take on breast cancer. In addition to landing big players to direct each of the shorts, the movie features the likes of Patricia Clarkson (Pieces of April), Rosario Dawson (Sin City), Lyndsy Fonseca (Nikita), Ginnifer Goodwin (Big Love), Josh Holloway (Lost), Taylor Kinney (The Vampire Diaries), Jenifer Lewis (The Princess and the Frog), Jennifer Morrison (House M.D.), Kathy Najimy (WALL-E), Golden Globe Award winner Bob Newhart (Horrible Bosses), Annie Potts (Law & Order: SVU), Tracee Ellis Ross (Girlfriends), Emmy and Golden Globe winner Tony Shalhoub (Monk), and Emmy nominees Jeffrey Tambor (Arrested Development) and Jeanne Tripplehorn (Big Love).

Five premieres Monday, Oct. 10 at 9 p.m. and to promote the event, Moore, Aniston & Keys recently talked about the film, not to mention love, in Glamour. Now, SheKnows has the extended trailer here.


Image: Ghetty