Who would you like to see on Two and a Half Men?

Mar 10, 2011 at 6:52 p.m. ET

With Charlie Sheen burning every bridge back to Two and a Half Men, the chatter about who might replace him continues.

With all this talk about filling the "winner" slot, SheKnows wondered who our readers would like to see. As previously reported, names like Rob Lowe and John Stamos were being bandied about. Now that Lowe is off the list, Matt Dillon has joined it, but hey, let's think outside of the box!

Two and a Half Men

Many believe Charlie Sheen is Two and a Half Men and a recast won't even work. SheKnows may have to agree, but we're trying to keep an open mind. After all, there's a whole cast and crew depending on that gig, and a country ready to tune in. So who might keep us coming back?

Before we get started, we should advise that Rob Lowe has been removed from the list of contenders.Parks and Recreationhead honcho Mike Schur told a crowd at the 28th Annual William S. Paley Television Festival that Lowe is locked into a "multiyear contract" with his show.

It's also important to note that since the Two and a Half Men character Charlie Harper was created for Sheen, it's unlikely someone will assume that role. In addition, be warned that while the name of the show would indicate another man for the job, SheKnows would never compile a list without ladies!

First up, however, is another dashing dude. Okay, perhaps "darling" is the word here. As many recall, Sheen jumped in to save Sin City when Michael J. Fox had to leave for medical reasons. Now that Fox has gotten a handle on living with Parkinson's disease, maybe he can come in to save the day.

SheKnows can also get with the idea of Stamos and Dillon, but we want to throw Robert Downey Jr. into the conversation! He went to high school with Two and a Half Men star Jon Cryer back in the day. Of course, that doesn't mean they knew each other, but it sounds like a fun combo, doesn't it? If only Downey could be lured to TV...

Jenny McCarthy

Jenny McCarthy?

If indeed Two and a Half Men brings in someone new, the key to making it work would be instant chemistry, so how about a proven match for Cryer? There are a slew of past guest stars to consider, including Enrique Iglesias, Michael Clarke Duncan, Eddie Van Halen, Steven Eckholdt, Martin Mull, Brooke Shields, Morgan Fairchild and wildly funny Jenny McCarthy.

Then, of course, there were also visits from Sheen family members Emilio Estevez and Martin Sheen. Martin played one of Evelyn's men, while Emilio played Charlie's wild and crazy wingman who came for a visit and died. Hey, if soaps can bring them back from the dead, why not sitcoms?

Going back to McCarthy, SheKnows can definitely see her bringing some of Charlie's hedonism to Men, but another female front runner is Sheen's Spin City costar Heather Locklear. She has proven comedy chops and played Alan's divorce attorney in the first season of Two and a Half Men. Locklear's sexy vibe makes her a viable candidate to play the female version of ladies' man Charlie.

Cryer also gave voice to characters in Pamela Anderson's Stripperella. She'sanother sexifier who could play the player in the Two and a Half Men lineup, but does she have comedy chops?

We've already seen Pretty in Pink costar Harry Dean Stanton mentioned. He did a cameo as one of Charlie's poker buddies, along with Sean Penn. Either one of those guys could be an interesting call and might even work, but...

What about reuniting Cryer with Duckie's first love, Molly Ringwald? Ringwald recently did serious time on The Secret Life of the American Teenager, but got her start with John Hughes laughs. Could she make it happen in primetime?

What about fellow brat pack alum Judd Nelson, who guested on Men as one of Alan's girlfriend's exes? With Entourage winding down, how about giving the role to Jeremy Piven? Or perhaps Two and a Half Men can lure Woody Harrelson back to the small screen!

Two and a Half Men could shake up the laughs in a big way by bringing in Duane Martin. Back in '98, Cryer worked with funnyman Martin, who is currently connected to The Paul Reiser Show. If Martin signed on to Two and a Half Men, he'd certainly bring a new flavor to the Malibu comedy.

Cryer also did a stint on Hannah Montana. Miley Cyrus would also change the dynamic entirely, while bringing a massive new audience to an already popular show.

Whoever Two and a Half Men adds to the mix, Sheen has already given some advice. "What I would advise them to do… is just make it their own," he told Dan Patrick. "Don't, don't, don't think about anything that I've done brilliantly on the show for 177,000 episodes… I would just tell them, make it your own."

Leave a comment to let us know what you think. Is one of these folks a real contender, or is there someone SheKnows has missed?