Giuliana Rancic pregnancy struggle involves 60 shots

Nov 19, 2010 at 11:49 a.m. ET

E! host Giuliana Rancic and her husband Bill are trying to get pregnant again after their miscarriage earlier this year.

Giuliana and Bill Rancic

Giuliana Rancic is undergoing IVF treatments to get pregnant -- and that involves over 60 shots a month!

"Sometimes I have to get [injections] 21 days in a row, three times a day," she told UsMagazine.com. "It's a lot. But you've got to do it."

Bill is her nurse!

The 36-year-old E! host and star of the reality show Giuliana and Bill said that her hubby is her personal nurse. "Bill could honestly be on Grey's Anatomy," Giuliana joked. "He could be McRancic."

"I give a pretty good shot," Bill, 39, said.

The couple has been trying to get pregnant, and even suffered a miscarriage earlier this year.

"We took a much needed break from all the fertility stuff to connect with each other again. We had been trying for so long to have a child that the whole process had consumed us. A break was crucial to make sure our marriage stayed strong and as fun as it always was," Bill told Popeater.com. Read the Giuliana and Bill's full love story >>

The couple said they are ready to try again. "The good news is that IVF did work as we did get pregnant," Giuliana Rancic said.

If it doesn't work, they said they may be open to other options. "We've gotten probably 40 women who have offered to be surrogates," she said.

read on for More Giuliana and Bill

Giuliana Rancic speaks about infertility
Giuliana and Bill talk devastating miscarriage
Giuliana says age and weight affected fertility

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