Well, it's just a clip from their new flick, Scary Movie V. The two, who play themselves in the film, are shown lying in bed together. Lohan's "sobriety monitor" then goes off, and the pair are attacked by supernatural forces.
Directed by Malcolm Lee, Scary Movie V stars Ashley Tisdale, Snoop Dogg, Katt Williams, Terry Crews, Simon Rex, Jerry O'Connell and Heather Locklear.
It features send-ups of a wide range of films, including Paranormal Activity, Mama, Inception and Black Swan.
Lohan and Sheen have small roles in the comedy, and based on the trailer, the pair poke fun of themselves in the film.
Sheen previously appeared in the third and fourth Scary Movie films, while Lohan is new to the franchise.
Neither actor is a stranger to farcical comedy. Sheen appeared in the well-received Hot Shots spoofs, while Lohan mocked her hard-drinking public persona in the violent satire Machete. Coincidentally, Sheen will take on the role of the president in the forthcoming Machete Kills.
Lohan and Sheen recently teamed up for the small screen when Lohan filmed a guest spot on his FX series, Anger Management.
Considering the fact that the first four Scary Movie films took in a whopping $800 million at the box office, the small-udget film will likely fare well when it's released on April 12.
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