After a six-year acting break, Renée Zellweger is jumping back into the film game in a big way. Not only did she release Bridget Jones's Baby in 2016, but her new movie, Same Kind of Different As Me, looks to be the kind of role we love for Zellweger: A woman who knows what she wants and is just adorably quirky enough that you never say no.

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In the film, Zellweger stars opposite Greg Kinnear. They play a struggling married couple who befriends a homeless man, a friendship that takes them on a journey that will change their lives. The film is based on the book of the same name, which also happens to be based on a true story.

Needless to say, the trailer alone is enough to get the tears flowin'.

This isn't the first time Zellweger and Kinnear have shared the screen together. They also appeared together in 2000's Nurse Betty.

Of course, a lot has happened for the two actors since 2000. Zellweger won herself an Oscar for her role in Cold Mountain and Kinnear has appeared in dozens of films and television shows like The Kennedys, which earned him an Emmy nomination.

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But it seems their careers have taken them full circle with Same Kind of Different As Me and SheKnows has an exclusive look. In the clip for the film, Zellweger's character, Deborah, is ready to get down to business helping at a homeless shelter. Her husband, Ron (Kinnear), isn't so keen on the idea, but, well, as another shelter helper says as he hands Ron an apron, "My wife wore the pants too."

Same Kind of Different As Me hits theaters on Oct. 20, 2017.