On Thursday, the "Lose Yourself" rapper took aim at Jenner in a freestyle rap on the SiriusXM radio show Sway in the Morning, and his lyrics are pretty harsh.
"This is a true statement, I see the bitch in you, Caitlyn," he rapped. "I keep the pistol tucked like Bruce Jenner's d*** / No disrespect, though, not at all/ No pun intended, that took a lot of balls."
Jenner was not his only celeb victim, though. He also took aim at comedian Bill Cosby.
"I made monopoly off misogyny," he said. "Sodomy, how many chocolatey Jell-O pops can he possibly lace, walking atrocity / No wonder you scoff at me, it's obvious I'm as off-putting as Bill Cosby is."
Eminem, whose real name is Marshall Bruce Mathers III, has no doubt upset many people with his rap, but he made a point to clarify that his rap was meant to be all in jest.
"The rhyme, by the way, it's all in fun," he explained, as reported by Sway's Universe. "I just say shit to say it. I don't even know if there's anything. …It's one of them things that's not … It's very rarely, very rarely personal. Put it this way, if it was ever personal, someone would know it. It's all in fun."
Watch the video below for more, but be warned: It's profanity-laden.
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