Symptoms of autism REVERSED in mice by 100-year-old drug

3 years ago

NOW THIS is pretty interesting. 

Researchers at the University of California-San Diego School of Medicine have found a way to reverse the symptoms of autism in mice (which are actually very similar to humans in brain structure).

Using a 100-year-old drug called "suramin," which used to be used to treat something called "African sleeping sickness," they blocked the signaling pathway of damaged cells. 

This is important because when this signal pathway happens, the cells go into "cell danger response," which is a a defense tactic that can cause permanent damage. Basically, if the cell is damaged (by bacteria, virus or chemicals), it stiffens its membrane, which changes its metabolic processes and cuts off communication (or reduces it) with other cells.

Anyway, about the suramin: Lo and behold, the mice began behaving normally! 

I can see this having potential for far more than autism, but for now, the researchers have been granted permission to do a small clinical trial with kids with ASD.

Here's what I read:

http://www.medicalnewstoday.com/articles/278364.php

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